A) The size and shape of the cells that make up the stratum spinosum,as well as the thick bundles of intermediate filaments.
B) The dermis is the thickest portion of the skin and water cannot pass through it.
C) Lamellated granules of the cells of the stratum granulosum,a glycolipid that is secreted into extracellular spaces.
D) Fat associated with skin prevents water loss.
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